Supplementary Data

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Figure 1

Results of the proposed molecular network analysis

• Molecular network analysis step 1: changed phosphopeptides in FTLD/AD models [Microsoft Excel(.xlsx)]
• Molecular network analysis step 2: PPI-based molecular networks in FTLD/AD models at 1,3 and 6 months >> [JPEG and CSML]
• Molecular network analysis step 3: core node selection by network centrality [Microsoft Excel(.xlsx)]
• Molecular network analysis step 4: core edge selection by correlation value [Microsoft Excel(.xlsx)]
• Molecular network analysis step 5: Core networks of FTLD/AD models [Microsoft Excel(.xlsx)]
• Molecular network analysis step 6: common core network between FTLD and AD [Microsoft Excel(.xlsx)]

Extended Data Figure 5

APP-KI as external hold-out data of AD models

• Changed phosphopeptides in APP-KI [Microsoft Excel(.xlsx)]
• Betweenness centrality in PPI-based network of APP-KI [Microsoft Excel(.xlsx)]
• Correlation values of core edges in APP-KI [Microsoft Excel(.xlsx)]